• General dentistry · Sep 2007

    Case Reports

    Resolution of an oral ulcer secondary to acetaminophen/hydrocodone withdrawal.

    • Ramesh Balasubramaniam, Po-Ching Lin, Dean K White, and Juan F Yepes.
    • Orofacial Pain Center, College of Dentistry and Medicine, University of Kentucky, Lexington, USA.
    • Gen Dent. 2007 Sep 1;55(5):441-4.

    AbstractAcetaminophen/hydrocodone is a common non-opioid/opioid analgesic indicated for the treatment of moderate to severe pain. The following report depicts a unique case involving a 57-year-old woman with a persistent, painful oral ulcer that was unresponsive to standard treatments. The ulcer was resolved when the patient discontinued acetaminophen/hydrocodone use. The cause of the ulcer is unclear but it was speculated to result from a systemic hypersensitivity reaction to acetaminophen/hydrocodone.

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