• Indian J Pediatr · Jan 2010

    Review

    Gastrointestinal bleed with clopidogrel and aspirin.

    • Vikas Kohli, Anupam Sibal, Sujit Choudhary, and Raja Joshi.
    • Pediatric Cardiology and Congenital Cardiac Centre, Indraprastha Apollo Hospital, New Delhi, India.
    • Indian J Pediatr. 2010 Jan 1;77(1):101-2.

    AbstractAnti-platelet drugs have been used to prevent thrombosis of systemic to pulmonary artery shunts. Aspirin has traditionally been used. Clopidogrel is being studied as an alternative and in combination with aspirin for shunt patients. We report a near fatal gastro-intestinal bleed in a patient with shunt and on aspirin and clopidogrel. This combination has been known to produce similar bleeds. The authors recommend caution in combining them. Prospective studies currently underway should evaluate this aspect of the antiplatelet drugs.

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