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The veterinary journal · Oct 2013
Incidence of intraoperative hypotension during isoflurane-fentanyl and propofol-fentanyl anaesthesia in dogs.
- Tomoya Iizuka, Masatoshi Kamata, Masashi Yanagawa, and Ryohei Nishimura.
- Laboratory of Veterinary Emergency Medicine, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
- Vet. J. 2013 Oct 1;198(1):289-91.
AbstractMost anaesthetic and analgesic drugs affect the cardiovascular system and can cause intraoperative hypotension (IOH). This study aimed to compare the incidence of IOH in anaesthetised dogs when isoflurane-fentanyl was used, compared to propofol-fentanyl. Intraoperative hypotension was defined as an episode of mean blood pressure below 60 mmHg for more than 5 min during anaesthesia. The incidence of IOH was 65.3% for isoflurane-fentanyl and 27.6% for propofol-fentanyl. The adjusted odds ratio for IOH when propofol-fentanyl was compared to isoflurane-fentanyl was 0.2 (95% CI 0.11-0.38). These results suggest that propofol-fentanyl is associated with a lower risk of IOH than isoflurane-fentanyl anaesthesia.Copyright © 2013 Elsevier Ltd. All rights reserved.
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