• Anesth Essays Res · Jan 2013

    Review

    Improving neurological outcome after cardiac arrest: Therapeutic hypothermia the best treatment.

    • Suchitra Malhotra, Satyavir S Dhama, Mohinder Kumar, and Gaurav Jain.
    • Department of Anaesthesia and Intensive Care, Teerthankar Mahaveer Medical College, Moradabad, Uttar Pradesh, India.
    • Anesth Essays Res. 2013 Jan 1;7(1):18-24.

    AbstractCardiac arrest, irrespective of its etiology, has a high mortality. This event is often associated with brain anoxia which frequently causes severe neurological damage and persistent vegetative state. Only one out of every six patients survives to discharge following in-hospital cardiac arrest, whereas only 2-9% of patients who experience out of hospital cardiac arrest survive to go home. Functional outcomes of survival are variable, but poor quality survival is common, with only 3-7% able to return to their previous level of functioning. Therapeutic hypothermia is an important tool for the treatment of post-anoxic coma after cardiopulmonary resuscitation. It has been shown to reduce mortality and has improved neurological outcomes after cardiac arrest. Nevertheless, hypothermia is underused in critical care units. This manuscript aims to review the mechanism of hypothermia in cardiac arrest survivors and to propose a simple protocol, feasible to be implemented in any critical care unit.

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