• N. Z. Med. J. · Apr 2010

    Physiology of the placebo effect, and the evidence for changes in brain metabolism.

    • Martin Wallace.
    • 24 Stonebridge Estate, Wallace Road, R D 9, Hamilton 3289, New Zealand. mart-jan@xtra.co.nz
    • N. Z. Med. J. 2010 Apr 9;123(1312):54-60.

    AbstractPlacebo effects are accompanied by localised changes in brain physiology. Variation between individuals in the extent of a placebo effect is due to genetic variation in brain enzyme activity. Some of the effect of any active drug is a placebo effect, and this should be considered in the evaluation of overall action.

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