• Pathologie-biologie · Feb 2014

    Case Reports

    [Macrophage activation syndrome: rare complication of murine typhus].

    • C Loussaief, A Toumi, H Ben Brahim, A Aouam, M Kairallah, and M Chakroun.
    • Service des maladies infectieuses, hôpital Fattouma Bourguiba, 5019 Monastir, Tunisie. Electronic address: loussaief10@yahoo.fr.
    • Pathol. Biol. 2014 Feb 1;62(1):55-6.

    IntroductionTyphi is one of the rickettsial species endemic in the Mediterranean countries and is associated with the zoonotic infection of murine typhus, which may have a complicated course especially in adult patients. The association with macrophage activation syndrome (MAS) has rarely been reported in the medical literature.Case ReportWe describe a case of murine typhus in a diabetic woman complicated with MAS, who was effectively treated with cyclin and parenteral immunoglobulin.ConclusionThe murine typhus can be exceptionally complicated with SAM. This infection should be suspected in front of the discovery of SAM.Copyright © 2013 Elsevier Masson SAS. All rights reserved.

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