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J. Clin. Microbiol. · Jan 2014
High nasal burden of methicillin-resistant Staphylococcus aureus increases risk of invasive disease.
- Rupak Datta, Atia Shah, Susan S Huang, Eric Cui, Vinh Nguyen, Susan J Welbourne, Kathleen A Quan, and Lauri Thrupp.
- Health Policy Research Institute, University of California Irvine School of Medicine, Irvine, California, USA.
- J. Clin. Microbiol. 2014 Jan 1;52(1):312-4.
AbstractIn a retrospective cohort study of 1,140 patients harboring methicillin-resistant Staphylococcus aureus, the nasal burden was low in 31%, category 1+ to 2+ in 54%, and category 3+ to 4+ in 15%. There was a significant trend in infection risk with increasing nasal burden (P = 0.007). In multivariate models, high nasal burden remained significantly associated with invasive infection.
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