• Lei Pan, Peifang Zhang, and Qingshui Yin.
• Department of Orthopaedics Surgery, The People's Hospital of Foshan, Sanshui District, Foshan 528100, Guangdong Province, China.
• Int J Surg. 2014 Jan 1;12(5):534-7.

ObjectivesThis study aimed to compare the clinical efficacies of percutaneous endoscopic lumbar discectomy (PELD) and traditional open lumbar discectomy (OD).MethodsThe pre-operative and post-operative blood loss, hospital stays and wound sizes of the patients in the two groups were recorded. Enzyme-Linked immunosorbent assay was used to measure the changes of interleukin-6 (IL-6), C-reactive protein (CRP) and creatine phosphokinase (CPK) pre-operation and 1 h, 6 h, 12 h, 24 h and 48 h after corresponding surgery. Visual Analog Scale and Modified MacNab Criteria were used to assess post-operative results.ResultsPatients in the PELD group had less blood loss (p < 0.01), shorter hospitalization hours (p < 0.01) and smaller surgical wounds (p < 0.01) than the patients underwent traditional OD surgery. MacNab evaluated that the levels of satisfaction were above 90% in both groups post-operative six months. There was no significant difference in pain index between the two groups (p > 0.05). Furthermore, the levels of CRP, CPK and IL-6 in the PELD group were all lower than those in the OD group with a significant difference (p < 0.01).ConclusionThe PELD had less damage to human tissues than the traditional OD. PELD has a clear promotional value in clinical.Copyright © 2014 Surgical Associates Ltd. Published by Elsevier Ltd. All rights reserved.

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