• Isr Med Assoc J · Apr 2003

    Review

    Vasopressin in cardiac arrest and vasodilatory shock: a forgotten drug for new indications.

    • Ron Ben-Abraham, Eran Hadad, Avi A Weinbroum, Ori Efrati, and Gideon Paret.
    • Department of Anesthesiology and Critical Care, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
    • Isr Med Assoc J. 2003 Apr 1;5(4):272-6.

    AbstractVasopressin is a potent endogenous vasoconstrictor that increases blood pressure and systemic vascular resistance. The administration of exogenous vasopressin during closed and open cardiopulmonary resuscitation in humans was shown to be more effective than optimal doses of epinephrine in several clinical studies. We summarize here the recent experimental and clinical data on the use of vasopressin in cardiopulmonary resuscitation and septic shock. As the use of vasopressin in human resuscitation is now in its early stages, it is expected that accumulated future experience will shed more light regarding the risk-benefit aspects of its use.

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