-
Nephrol. Dial. Transplant. · Aug 2010
Review Case ReportsPulmonary alveolar proteinosis in a kidney transplant: a rare complication of sirolimus.
- Huseyin Kadikoy, Michael Paolini, Katafan Achkar, Wadi Suki, A Osama Gaber, Nabeel Anwar, Abdallah Jeroudi, Roberto Barrios, and Abdul Abdellatif.
- Department of Medicine, Baylor College of Medicine, Houston, TX, USA. hkadikoy@gmail.com
- Nephrol. Dial. Transplant. 2010 Aug 1;25(8):2795-8.
AbstractPulmonary alveolar proteinosis (PAP) has been associated with the immunosuppressant sirolimus in transplant patients. PAP is a progressive lung disease characterized by the accumulation of surfactant-like material in the lungs leading to decreased pulmonary function with shortness of breath and cough as common symptoms. We report a rare case of sirolimus-associated PAP in a kidney transplant recipient with a history of end-stage renal disease secondary to haemolytic uraemic syndrome (HUS) and review of the literature. Discontinuation of sirolimus and initiation of tacrolimus led to resolution of PAP without recurrence of HUS.
Notes
Knowledge, pearl, summary or comment to share?You can also include formatting, links, images and footnotes in your notes
- Simple formatting can be added to notes, such as
*italics*,_underline_or**bold**. - Superscript can be denoted by
<sup>text</sup>and subscript<sub>text</sub>. - Numbered or bulleted lists can be created using either numbered lines
1. 2. 3., hyphens-or asterisks*. - Links can be included with:
[my link to pubmed](http://pubmed.com) - Images can be included with:
 - For footnotes use
[^1](This is a footnote.)inline. - Or use an inline reference
[^1]to refer to a longer footnote elseweher in the document[^1]: This is a long footnote..