• Rev Bras Cir Cardiovasc · Apr 2008

    Review

    Postoperative cognitive dysfunction after cardiac surgery.

    • José Fernando Vilela Martin, Renan Oliveira Vaz de Melo, and Letícia Pinheiro de Sousa.
    • Departamento de Medicina, FAMERP. vilelamartin@uol.com.br
    • Rev Bras Cir Cardiovasc. 2008 Apr 1;23(2):245-55.

    AbstractPostoperative cognitive dysfunction is frequent in cardiac surgeries leading to major consequences. The physiopathological processes involved in this condition are still not completely elucidated, despite the multifactor character. Besides pre-operative factors such as age and education, some intra-operative factors are also of extreme importance. However, according to a vast literature on the subject, these factors are not capable to clarify the totality of the cases, taking us to a genetic base for this neurological sequel. In this revision, we briefly assess the factors involved in this cognitive dysfunction as well as discuss the pharmacotherapy in the prevention of this event.

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