• American family physician · Sep 1995

    Review

    Fibromyalgia: more than just a musculoskeletal disease.

    • D J Clauw.
    • Georgetown University School of Medicine, Washington, D.C., USA.
    • Am Fam Physician. 1995 Sep 1;52(3):843-51, 853-4.

    AbstractFibromyalgia is a common condition characterized by diffuse musculoskeletal pain and fatigue. The syndrome is defined by the presence of musculoskeletal tender points on physical examination. Additionally, persons with this syndrome have a high incidence of headaches, ocular and vestibular complaints, paresthesias, esophageal dysmotility, "allergic" symptoms, irritable bowl syndrome, genitourinary symptoms and affective disorders. Recent research has revealed a number of objective biochemical, hormonal and neurotransmitter abnormalities associated with fibromyalgia, making it a clearly identifiable condition. These abnormalities may clarify our understanding of the pathogenesis and treatment of fibromyalgia.

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