• Anita Perpetua Carvalho Rocha, Guilherme Antonio Moreira Barros, Jedson dos Santos Nascimento, Kleber Pimentel Santos, Lilian Mendes de Vasconcelos, and Pedro Augusto Costa Rebouças de Castro.
• Hospital Santa Izabel, Santa Casa de Misericórdia da Bahia, Rua Pacífico Pereira 381/1303, Salvador, Bahia, Brazil. anitaperpetuacrc@yahoo.com.br
• Arq. Bras. Cardiol. 2011 Mar 1;96(3):219-26.

BackgroundSedation for heart catheterization has been a cause for concern. Benzodiazepines, alpha-2 adrenergic agonists and opioids are used for this purpose. However, each drug has advantages and disadvantages.ObjectiveTo evaluate the efficacy of sufentanil and clonidine as sedative in patients undergoing heart catheterization, observing their impact on hemodynamic and respiratory parameters, the presence of side effects and satisfaction of the patient and interventional cardiologist with the examination.MethodsThis is a prospective, double-blind, randomized and controlled clinical trial involving 60 patients who received 0.1 µg/kg of sufentanil or 0.5 µg/kg of clonidine before heart catheterization. The score of sedation according to the Ramsay scale, the need for use of midazolam, side effects and hemodynamic and respiratory parameters were recorded, with the data being analyzed at 06 different moments.ResultsThe behavior of blood pressure, heart rate and respiratory rate was similar in both groups, but, at moment 2, the patients in the sufentanil group (Group S) had a lower sedation score on the Ramsay scale, and the peripheral oxyhemoglobin saturation was lower than in the clonidine group (Group C) at time 6. Patients in Group S had higher incidence of nausea and vomiting after surgery than patients in Group C. Patient satisfaction was higher in the clonidine group. The interventional cardiologists were satisfied in both groups.ConclusionSufentanil and clonidine were effective as sedative in patients undergoing heart catheterization.

33 keywords...

hide…