• Pain · May 2001

    Case Reports

    Treatment of central post-stroke pain with oral ketamine.

    • P G Vick and T J Lamer.
    • Department of Anesthesiology, University of North Carolina at Chapel Hill, Campus Box # 7010, Chapel Hill, NC 27599-7010, USA. pvick@aims.unc.edu
    • Pain. 2001 May 1;92(1-2):311-3.

    AbstractCase report of 68 year old female with central post-stroke pain successfully treated with oral ketamine. The patient's pain was refractory to conventional pain treatments and she had persistent right hemi-body neuropathic pain with allodynia and hyperalgesia. An intravenous ketamine trial, followed by oral ketamine with titration to 50mg three times a day was beneficial in decreasing allodynia and hyperalgesia, as well as improving functional capabilities. Known side effects including dysphoria, hallucinations, and paranoid feelings were attenuated with benzodiazepines.

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