-
- I A Vinogradova, A V Bukalev, M A Zabezhinskiĭ, A V Semenchenko, and V N Anisimov.
- Vopr Onkol. 2008 Jan 1;54(1):70-7.
AbstractThe effect of various light regimens--standard, 12 hrs light:12 hrs darkness, natural lighting in the North-West of Russia and constant illumination--on homeostasis, life span and spontaneous tumorigenesis has been studied in male rats. It was shown that constant exposure or natural lighting involved accelerated aging as evaluated by coefficient of homeostatic stability and survival curves shifting to the left. Constant illumination was followed by a significantly faster spontaneous tumorigenesis as compared with standard lighting. Nocturnal administration of melatonin with drinking water (10 mg/l) prevented the adverse effects of constant and natural lighting on homeostasis and inhibited spontaneous tumorigenesis, particularly, that in the hemopoietic system.
Notes
Knowledge, pearl, summary or comment to share?You can also include formatting, links, images and footnotes in your notes
- Simple formatting can be added to notes, such as
*italics*,_underline_or**bold**. - Superscript can be denoted by
<sup>text</sup>and subscript<sub>text</sub>. - Numbered or bulleted lists can be created using either numbered lines
1. 2. 3., hyphens-or asterisks*. - Links can be included with:
[my link to pubmed](http://pubmed.com) - Images can be included with:
 - For footnotes use
[^1](This is a footnote.)inline. - Or use an inline reference
[^1]to refer to a longer footnote elseweher in the document[^1]: This is a long footnote..