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J. Heart Lung Transplant. · Aug 1999
Case ReportsSuccessful eradication of mucormycosis occurring in a pulmonary allograft.
- D A Hunstad, A H Cohen, and J W St Geme.
- Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri 63110, USA.
- J. Heart Lung Transplant. 1999 Aug 1;18(8):801-4.
AbstractThe zygomycetes are saprophytic fungi that rarely cause disease in the normal human host. In immunocompromised individuals, these organisms can cause invasive infections, collectively called mucormycosis. Mucormycosis is associated with a high mortality rate, especially in organ transplant recipients. In this report, we describe the first case of successfully treated mucormycosis involving a pulmonary allograft. Treatment consisted of surgical excision of the affected lobe and chest wall and lipid-complex amphotericin B. The lipid complex formulation permitted a prolonged course of therapy that was likely critical to eradication of the infection.
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