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- Takahiro Tsuji, Keiko Morikawa, Taichi Hirano, Hiroshi Yamasaki, and Hiroyuki Tsuda.
- Division of Hematology and Oncology, Kumamoto City Hospital.
- Rinsho Ketsueki. 2013 Aug 1;54(8):769-71.
AbstractAn 82-year-old female with a history of aortic dissection was admitted to our hospital for evaluation of thrombocytopenia and a bleeding tendency. Blood coagulation test data demonstrated that the patient had disseminated intravascular coagulation (DIC) secondary to aortic dissection. We initiated anti-fibrinolytic therapy with tranexamic acid. After this anti-fibrinolytic therapy, thrombocytopenia and the levels of fibrinogen and fibrinogen degradation products improved. In addition, we reviewed 7 other patients who were treated with tranexamic acid for DIC associated with aortic dissection. Anti-fibrinolytic therapy with tranexamic acid is effective for treating DIC secondary to aortic dissection.
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