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- N S Lincoff, P P Rath, and M Hirano.
- Department of Neurology and Ophthalmology, School of Medicine and Biomedical Sciences, State University of New York, Buffalo, USA.
- J Neuroophthalmol. 1998 Mar 1;18(1):17-20.
AbstractThis article describes the effects of topically applied capsaicin (a nociceptive substance-P suppressor) in patients with neuropathic periocular or facial pain. Peripheral neuropathic pain is a major cause of periocular or facial discomfort and usually follows injury to a subcutaneous peripheral nerve. Though the damage is local, the pain tends to radiate. We studied three patients who complained of a 2- to 30-year history of fluctuating pain in the periocular area. All three had an area of point tenderness that responded to the topical application of capsaicin cream.
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