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Rev Bras Ter Intensiva · Jun 2010
Mild therapeutic hypothermia after cardiac arrest: mechanism of action and protocol development.
- Tatiana Helena Rech and Sílvia Regina Rios Vieira.
- Hospital Dom Vicente Scherer do Complexo Hospitalar Santa Casa, Porto Alegre, RS, Brasil.
- Rev Bras Ter Intensiva. 2010 Jun 1;22(2):196-205.
AbstractCardiac arrest is a high mortality event and the associated brain ischemia frequently causes severe neurological damage and persistent vegetative state. Therapeutic hypothermia is an important tool for the treatment of post-anoxic coma after cardiopulmonary resuscitation. It has been shown to reduce mortality and to improve neurological outcomes after cardiac arrest. Nevertheless, hypothermia is underused in critical care units. This manuscript aims to review the hypothermia mechanism of action in cardiac arrest survivors and to propose a simple protocol, feasible to be implemented in any critical care unit.
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