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- Teresa L Smith and Thomas P Bleck.
- Neuroscience Critical Care, and Clinical Instructor of Neurology, University of Virginia School of Medicine, Charlottesville, Virginia, USA. tls2u@virginia.edu
- Crit Care. 2002 Oct 1; 6 (5): 377380377-80.
AbstractHypothermia as a protectant of neurologic function in the treatment of cardiac arrest patients, although not a new concept, is now supported by two recent randomized, prospective clinical trials. The basic science research in support of the effects of hypothermia at the cellular and animal levels is extensive. The process of cooling for cerebral protection holds potential promise for human resuscitation efforts in multiple realms. It appears that, at least, those patients who suffer a witnessed cardiac arrest with ventricular fibrillation and early restoration of spontaneous circulation, such as those who were included in the European and Australian trials (discussed here), should be considered for hypothermic therapy.
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