• Support Care Cancer · Jan 2014

    Rest/activity rhythm is related to the coexistence of pain and sleep disturbance among advanced cancer patients with pain.

    • Chen-Lai Ma, Wen-Pei Chang, and Chia-Chin Lin.
    • Department of Anesthesiology, Tungs' Taichung MetroHarbor Hospital, Taichung, Taiwan.
    • Support Care Cancer. 2014 Jan 1;22(1):87-94.

    PurposeThis study aimed to explore the relationships among pain, sleep disturbance, and circadian rhythms in advanced cancer patients.MethodsThis cross-sectional study was conducted in 68 cancer patients from the oncology inpatient unit of a teaching hospital. Their demographic and medical characteristics, questionnaire surveys, including Brief Pain Inventory-Chinese version and Pittsburgh Sleep Quality Index Taiwanese version, and sleep logs and actigraphic recordings in consecutive 3 days and nights were collected and analyzed.ResultsThe mean (SD) scores for autocorrelation coefficient at 24 h (r24) and dichotomy index (IConclusionsThe rest/activity rhythm influences the coexisting pain and sleep disturbances. Pain functions as a complete mediator in their relationship. Interventions that improve rest/activity rhythms may improve the management of pain and sleep disturbances in cancer patients.

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