• J. Am. Coll. Cardiol. · Jun 2009

    Review

    Diagnosis and assessment of pulmonary arterial hypertension.

    • David B Badesch, Hunter C Champion, Miguel Angel Gomez Sanchez, Marius M Hoeper, James E Loyd, Alessandra Manes, Michael McGoon, Robert Naeije, Horst Olschewski, Ronald J Oudiz, and Adam Torbicki.
    • Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Health Sciences Center, Denver, Colorado 80045, USA. David.Badesch@uchdenver.edu
    • J. Am. Coll. Cardiol. 2009 Jun 30;54(1 Suppl):S55-66.

    AbstractThe diagnosis and assessment of pulmonary arterial hypertension is a rapidly evolving area, with changes occurring in the definition of the disease, screening and diagnostic techniques, and staging and follow-up assessment. The definition of pulmonary hypertension has been simplified, and is now based on currently available evidence. There has been substantial progress in advancing the imaging techniques and biomarkers used to screen patients for the disease and to follow up their response to therapy. The importance of accurate assessment of right ventricular function in following up the clinical course and response to therapy is more fully appreciated. As new therapies are developed for pulmonary arterial hypertension, screening, prompt diagnosis, and accurate assessment of disease severity become increasingly important. A clear definition of pulmonary hypertension and the development of a rational approach to diagnostic assessment and follow-up using both conventional and new tools will be essential to deriving maximal benefit from our expanding therapeutic armamentarium.

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