• Intensive care medicine · Jan 2008

    Hyponatremia in neurological patients: cerebral salt wasting versus inappropriate antidiuretic hormone secretion.

    • Serge Brimioulle, Carlos Orellana-Jimenez, Adel Aminian, and Jean-Louis Vincent.
    • Department of Intensive Care, Erasme University Hospital, Free University of Brussels, Lennik Road 808, 1070 Brussels, Belgium. serge.brimioulle@ulb.ac.be
    • Intensive Care Med. 2008 Jan 1;34(1):125-31.

    ObjectiveTo assess whether hyponatremia in acute neurological patients is associated with the syndrome of inappropriate antidiuretic hormone secretion (SIADH) or with the cerebral salt-wasting syndrome (CSWS).DesignClinical, controlled, prospective study.SettingDepartment of intensive care of a tertiary care academic hospital.PatientsForty acute neurological patients with hyponatremia suggesting SIADH or CSWS (20) or with normonatremia (20).InterventionsNone.Measurements And Main ResultsMeasurement of clinical and biological variables. Measurement of blood, plasma, and red blood cell volumes to discriminate SIADH and CSWS. Renal, adrenal and thyroid functions were normal in all patients. Average blood, plasma, and red blood cell volumes were 54, 37 and 17ml/kg in control patients and 54, 37 and 18ml/kg in hyponatremic patients, respectively.ConclusionsThe adequate blood volumes in hyponatremic patients confirm the diagnosis of SIADH and do not support the concept of CSWS.

      Pubmed     Full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…