• Sayeed Attar, Walter R Bowles, Michael K Baisden, James S Hodges, and Scott B McClanahan.
• Division of Endodontics, University of Minnesota School of Dentistry, Minneapolis, Minnesota, USA.
• J Endod. 2008 Jun 1;34(6):652-5.

AbstractThis study compares single-dose ibuprofen pretreatment for postoperative endodontic pain. Thirty-nine emergent patients were randomly assigned to 3 groups: placebo, ibuprofen tablets, or ibuprofen liquigels. Patients recorded their pain levels before and at the end of treatment, then every 6 hours for 24 hours after administration of the medications and standard endodontic treatment. Pain evaluations by using 3 pain scales (visual analog scale [VAS], category, and Heft-Parker) were highly correlated, suggesting the rationale for only using one pain scale in pain studies. No significant differences in postoperative pain levels were found between either single-dose ibuprofen formulation or the placebo control group (P = .84). Patients treated with calcium hydroxide versus obturation did not differ in postoperative pain levels (P = .44). This study suggests that single-dose pretreatment analgesia alone in endodontic pain patients will not significantly reduce postoperative pain below the reduction in pain from endodontic treatment.

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