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- R E Smeets, P G Melman, J J Hoffmann, and A W Mulder.
- Department of Internal Medicine, Catharina Hospital, Eindhoven, The Netherlands.
- J. Intern. Med. 1991 Oct 1; 230 (4): 351354351-4.
AbstractEuropean physicians may occasionally be confronted with cases of snake venom poisoning. The increasing interest in snakes as pets has unfortunately resulted in the importation of a number of venomous snakes. We here report the third known case in the medical literature of a patient who was exposed to severe coagulopathy after being bitten by a 'harmless' ringsnake (Rhabdophis subminiatus). The prolonged bleeding diathesis and the complete depletion of fibrinogen observed in our patient are consistent with the presence of a factor X activator in the venom, as has been described in a murine model. In agreement with the two previous case reports, we found no evidence of severe organ damage, despite active intravascular coagulation.
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