• Ibrahim Sari, Vedat Davutoglu, Nazan Bayram, and Serdar Soydinc.
• Department of Cardiology, School of Medicine, Gaziantep University, Gaziantep, Turkey.
• Clin. Appl. Thromb. Hemost. 2008 Oct 1;14(4):486-8.

AbstractThrombus formation in a morphologically normal a aorta is a very rare event. A 50-year-old man with a history of chronic obstructive pulmonary disease, presented to the emergency department with pulmonary edema. Transthoracic and transesophageal echocardiography revealed a highly mobile, pedunculated floating thrombus in the descending thoracic aorta 3-4 cm distal to the origin of the left subclavian artery. The original lumen of the aorta was almost obliterated by the thrombus. The aortic wall was free of any atheroma. Thrombolytic treatment was administered, but 3 hours after starting streptokinase, he developed sudden and severe low-back pain accompanied by loss of lower-extremity pulses which were patent on admission. Cardiopulmonary arrest developed within an hour and the patient died despite resuscitation. The potential causes of aortic thrombus, the clinical spectrum that the patients may present, diagnostic methods, and therapeutic options are discussed.

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