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Neurosurg. Clin. N. Am. · Apr 1997
ReviewBrain attack. Acute therapeutic interventions. Free radical scavengers and antioxidants.
- E D Hall.
- CNS Diseases Research, Pharmacia & Upjohn, Incorporated, Kalamazoo, Michigan 49001, USA.
- Neurosurg. Clin. N. Am. 1997 Apr 1;8(2):195-206.
AbstractEvidence suggesting a role of oxygen radical-induced lipid peroxidation in global and focal ischemic brain damage is reviewed, and the potential for treatment of these conditions with antioxidant compounds is highlighted. This article also presents a basis for appreciating the pharmacologic mechanisms by which oxygen radical damage can be inhibited.
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