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Anesthesia and analgesia · Dec 2013
A retrospective assessment of the incidence of respiratory depression after neuraxial morphine administration for postcesarean delivery analgesia.
- Theresa R Crowgey, Jennifer E Dominguez, Cathleen Peterson-Layne, Terrence K Allen, Holly A Muir, and Ashraf S Habib.
- From the Anesthesiology-Womens Division, Duke University Medical Center, Durham, North Carolina.
- Anesth. Analg.. 2013 Dec 1;117(6):1368-70.
AbstractRespiratory depression can occur after neuraxial morphine administration. In the obstetric population, there are little data on respiratory depression after neuraxial morphine administration in women undergoing cesarean delivery. In this single-center, retrospective study in 5036 obstetric patients (mean body mass index = 34 kg/m) who underwent cesarean delivery and received neuraxial morphine, we did not identify any instances of respiratory depression requiring naloxone administration or rapid response team involvement. Therefore, the upper 95% confidence limit for respiratory depression in our study is 0.07% (1 event per 1429 cases).
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