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- Robert Goldberg, Joel M Gore, Bruce Barton, and Jerry Gurwitz.
- Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, Mass; Meyers Primary Care Institute, Worcester, Mass. Electronic address: Robert.Goldberg@umassmed.edu.
- Am. J. Med. 2014 May 1; 127 (5): 379384379-84.
AbstractWe provide an overview of the individual and combined clinical endpoints and patient-reported outcomes typically used in clinical trials and prospective epidemiological investigations. We discuss the strengths and limitations associated with the utilization of aggregated study endpoints and surrogate measures of important clinical endpoints and patient-centered outcomes. We hope that the points raised in this overview will lead to the collection of clinically rich, relevant, measurable, and cost-efficient study outcomes.Copyright © 2014 Elsevier Inc. All rights reserved.
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