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Paediatric anaesthesia · Jan 2014
ReviewBeyond survival; influences of blood pressure, cerebral perfusion and anesthesia on neurodevelopment.
- Mary Ellen McCann and Anton N J Schouten.
- Department of Anesthesiology, Perioperative and Pain Medicine, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA.
- Paediatr Anaesth. 2014 Jan 1;24(1):68-73.
AbstractNeonates have a higher perioperative mortality risk largely due to the degree of prior illness of the infants, the complexity of their surgeries, and infant physiology. It is important to consider contributing anesthetic factors during the perioperative period that may affect cerebral perfusion and neurocognitive outcome, such as alterations in hemodynamics and ventilation. Limitations of blood pressure as a marker for cerebral perfusion are discussed, as well as the effect of hypocapnia on the brain.© 2013 John Wiley & Sons Ltd.
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