• Rev Bras Cir Cardiovasc · Oct 2011

    Randomized Controlled Trial

    Retrograde autologous priming in cardiopulmonary bypass in adult patients: effects on blood transfusion and hemodilution.

    • Ricardo Vieira Reges, Walter Vilella de Andrade Vicente, Alfredo José Rodrigues, Solange Basseto, Lafaiete Alves Junior, Adilson Scorzoni Filho, César Augusto Ferreira, and Paulo Roberto Barbosa Évora.
    • Division of Thoracic and Cardiovascular Surgery, Department of Anatomy, Faculty of Medicine of Ribeirão Preto, Universidade de São Paulo, SP, Brazil.
    • Rev Bras Cir Cardiovasc. 2011 Oct 1;26(4):609-16.

    IntroductionRetrograde autologous priming (RAP) is a cardiopulmonary bypass (CPB) method, at low cost. Previous studies have shown that this method reduces hemodilution and blood transfusions needs through increased intra-operative hematocrit.ObjectiveTo evaluate RAP method, in relation to standard CPB (crystalloid priming), in adult patients.MethodsSixty-two patients were randomly allocated to two groups: 1) Group RAP (n = 27) of patients operated using the RAP and; 2) Control group of patients operated using CPB standard crystalloid method (n = 35). The RAP was performed by draining crystalloid prime from the arterial and venous lines, before CPB, into a collect recycling bag. The main parameters analyzed were: 1) CPB hemodynamic data; 2) Hematocrit and hemoglobin values; 3) The need for blood transfusions.ResultsIt was observed statistically significant fewer transfusions during surgery and reduced CPB hemodilution using RAP. The CPB hemodynamic values were similar, observing a tendency to use lower CPB flows in the RAP group patients.ConclusionThis investigation was designed to be a small-scale pilot study to evaluate the effects of RAP, which were demonstrated concerning the CPB hemodilution and blood transfusions.

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