• Prog. Brain Res. · Jan 2008

    Review

    The role of dopamine and serotonin in suicidal behaviour and aggression.

    • Erik Ryding, Mats Lindström, and Lil Träskman-Bendz.
    • Department of Clinical Neurophysiology, Karolinska Hospital, Huddinge, SE 141 52 Stockholm, Sweden. erik.ryding@karolinska.se
    • Prog. Brain Res. 2008 Jan 1;172:307-15.

    AbstractSerotonin and dopamine are two monoamines which are known to interact with each other. Their role for suicidal behaviour, aggression and mood are reviewed in this chapter. We found a substantial amount of evidence for the relevance of a serotonin and dopamine model of aggression, and for aggression as a major risk factor for suicide. Evidence was found that serotonin and dopamine also may be involved in depressed mood, and possibly the individual's ability to cope with imminent suicidality.

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