• J H Judkins, T G Dray, and R N Hubbell.
• Department of Surgery, University of Vermont, Burlington, USA.
• Arch Otolaryngol. 1996 Sep 1;122(9):937-40.

ObjectiveTo determine the occurrence of posttonsillectomy bleeding in patients who received intraoperative ketorolac tromethamine.DesignRetrospective analysis.SettingAcademic tertiary care center.PatientsThree hundred eleven patients who underwent tonsillectomy in an 18-month period.Main Outcome MeasureOccurrence of bleeding complications in patients who received ketorolac during tonsillectomy.ResultsFifty-eight of 311 patients who underwent tonsillectomy received intraoperative ketorolac with an overall postoperative bleeding rate of 17%. This high rate of bleeding complications compares with 4.4% in the remaining 253 patients who received traditional opioid analgesics.ConclusionsUntil further controlled studies have been conducted, the use of ketorolac in patients undergoing tonsillectomy should be avoided because of the increased incidence of postoperative bleeding complications.

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