-
Multicenter Study
Impaired long-term quality of life in survivors of severe sepsis : Chinese multicenter study over 6 years.
- K Zhang, X Mao, Q Fang, Y Jin, B Cheng, G Xie, H Li, L Yu, T Zhu, H Wang, X Liu, Y Zhang, N Zhang, T Lou, and X M Fang.
- Department of Anesthesiology, The First Affiliated Hospital, School of Medicine, Zhejiang University, QingChun road 79, 310003, Hangzhou, China.
- Anaesthesist. 2013 Dec 1; 62 (12): 9951002995-1002.
ObjectivesThe present study was undertaken to evaluate the long-term health-related quality of life (HRQOL) as well as the employment status in survivors of severe sepsis up to 6 years afterwards.Material And MethodsFrom January 2003 to December 2008 a total of 112 severe sepsis and 112 age, gender and Charlson comorbidity index-matched non-septic critically ill patients from 4 university hospital intensive care units (ICU) were enrolled in the study and 126 age and gender-matched community residents were interviewed as the community control group.ResultsA total of 66 (58.9 %) severe sepsis and 80 (71.4 %) non-sepsis critically ill patients survived during the long-term follow-up time. Between August and December 2010 a total of 75 patients including 42 survivors of severe sepsis and 33 critically ill controls completed the face-to-face interview. There were no differences in the long-term HRQOL in terms of Short-Form 36 criteria between severe sepsis and non-sepsis critically ill survivors. However, when compared with the community controls, HRQOL in survivors of severe sepsis showed a significantly and clinically meaningful decrease, with a lower physical functioning (p = 0.016), vitality (p = 0.037), role-emotional (p = 0.043), mental health (p = 0.038) and mental component scores (p = 0.042). In addition, the criteria returning to work at 1 year and at the time of interview in severe sepsis survivors were similar with those in critically ill survivors (60.5 % vs. 70.0 %, p = 0.41 and, 71.1 % vs. 76.7 %, p = 0.602).ConclusionsThe HRQOL in survivors of severe sepsis was impaired even up to 6 years after hospital discharge.
Notes
Knowledge, pearl, summary or comment to share?You can also include formatting, links, images and footnotes in your notes
- Simple formatting can be added to notes, such as
*italics*
,_underline_
or**bold**
. - Superscript can be denoted by
<sup>text</sup>
and subscript<sub>text</sub>
. - Numbered or bulleted lists can be created using either numbered lines
1. 2. 3.
, hyphens-
or asterisks*
. - Links can be included with:
[my link to pubmed](http://pubmed.com)
- Images can be included with:
![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
- For footnotes use
[^1](This is a footnote.)
inline. - Or use an inline reference
[^1]
to refer to a longer footnote elseweher in the document[^1]: This is a long footnote.
.