• Bmc Musculoskel Dis · Jan 2015

    Review Meta Analysis

    Anterior cervical discectomy and fusion may be more effective than anterior cervical corpectomy and fusion for the treatment of cervical spondylotic myelopathy.

    • Li Guan, Yong Hai, Jin-Cai Yang, Li-Jin Zhou, and Xiao-Long Chen.
    • Department of Orthopedics, Beijing Chao-Yang Hospital, Capital Medical University, Gong Ti Nan Lu 8#, Chao-Yang District, Beijing, 100020, People's Republic of China. guanli403@163.com.
    • Bmc Musculoskel Dis. 2015 Jan 1;16:29.

    BackgroundThis meta-analysis explored the efficacy and safety of anterior cervical corpectomy and fusion (ACCF) comparing to anterior cervical discectomy and fusion (ACDF) in treating cervical spondylotic myelopathy (CSM) patients.MethodsSeveral electronic databases were searched combined with manually searching. Thirteen randomized controlled studies were enrolled with 1,062 CSM patients, including 468 patients and 594 patients in the in the ACCF and ACDF group, respectively. The meta-analysis was then performed using the STATA 12.0 software. Crude standard mean difference (SMD) or odds ratio (OR) with their 95% confidence intervals (CI) were calculated.ResultsOur meta-analysis results revealed that CSM patients in ACDF group showed less blood loss than those in ACCF group (SMD = 1.21, 95% CI = 1.03 ~ 1.39, P < 0.001). The operation time of CSM patients in the ACDF group was also obviously shorter than those in ACCF group (SMD = 0.40, 95% CI = 0.23 ~ 0.57, P < 0.001). Furthermore, CSM patients in ACDF group had shorter hospital time than those in ACCF group (SMD = 0.45, 95% CI = 0.21 ~ 0.69, P < 0.001).ConclusionOur findings provide empirical evidence that ACDF may be more effective than ACCF for CSM treatment.

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