• Arjun A Dhawale, Suken A Shah, Petya Yorgova, Geraldine Neiss, Douglas J Layer, Kenneth J Rogers, Peter G Gabos, and Laurens Holmes.
• Department of Orthopedics, Nemours/Alfred I. duPont Hospital for Children, 1600 Rockland Rd, PO Box 269, Wilmington, DE 19899, USA.
• Spine J. 2013 Nov 1;13(11):1485-92.

Background ContextSurgeons continue to debate the need for a cross-link (CL) in posterior spinal instrumentation constructs with segmental pedicle screws in adolescent idiopathic scoliosis (AIS). Advantage of CLs is increased stiffness of the construct, and disadvantages include added expense and risk of late operative-site pain and pseudarthrosis.PurposeTo compare the effectiveness of using CLs versus using no cross-links (NCLs) in posterior segmental instrumentation in AIS.Study DesignRetrospective comparative study, level of evidence 3.Patient SampleSeventy-five AIS patients less than 21 years of age, who underwent posterior spinal instrumentation with segmental pedicle screws (25 with CLs and 50 with NCLs) at a single institution with 2-year follow-up, are described.Outcome MeasuresPhysiologic measures include imaging: thoracic and lumbar Cobb angles, correction rate, apical vertebral translation (AVT), and apical vertebral rotation (AVR); self-report measures include Scoliosis Research Society (SRS) domain outcome scores.MethodsPreoperative (pre-op) and postoperative first erect, 1-year, and 2-year follow-up radiographs were measured. Instrumentation-related complications and normalized SRS scores were recorded. Independent sample t test, χ(2) test, and repeated-measures analysis of variance were used for analyses.ResultsThe average age at surgery was 14 years, the mean pre-op Cobb angle was 57°, and the mean number of levels fused was 10.9. The groups were similar preoperatively with respect to age, sex, Lenke curve, Cobb angle, AVT, and Risser grade and were similar intraoperatively for levels fused and anchor density. There was no difference in AVR, Cobb angle, correction rate, or AVT between the groups (p>.05). Complications included one wound infection in the CL group and one painful scar in the NCL group. There were no differences in SRS domain scores.ConclusionWe observed no differences in maintenance of correction, SRS scores, and complications with or without cross-linking posterior segmental instrumentation in AIS patients over 2-year follow-up. Further follow-up is necessary.Copyright © 2013 Elsevier Inc. All rights reserved.

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