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Anesthesia and analgesia · Jan 2012
Randomized Controlled TrialBrief reports: plasma ropivacaine concentrations after ultrasound-guided rectus sheath block in patients undergoing lower abdominal surgery.
- Morito Wada, Masato Kitayama, Hiroshi Hashimoto, Tsuyoshi Kudo, Mihoko Kudo, Norikazu Takada, and Kazuyoshi Hirota.
- Department of Anesthesiology, Hirosaki University Graduate School of Medicine, Japan.
- Anesth. Analg.. 2012 Jan 1;114(1):230-2.
AbstractA rectus sheath block can provide postoperative analgesia for midline incisions. However, information regarding the pharmacokinetics of local anesthetics used in this block is lacking. In this study, we detail the time course of ropivacaine concentrations after this block. Thirty-nine patients undergoing elective lower abdominal surgery were assigned to 3 groups receiving rectus sheath block with 20 mL of different concentrations of ropivacaine. Peak plasma concentrations were dose dependent, and there were no significant differences in the times to peak plasma concentrations. The present data also suggested a slower absorption kinetics profile for ropivacaine after rectus sheath block than other compartment blocks.
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