• Ugeskrift for laeger · Jan 2011

    Review

    [Prevention of herpes zoster by vaccination].

    • Kristian Kofoed, Finn Rønholt, Jan Gerstoft, and Carsten Sand.
    • Dermato-venerologisk Afdeling D41, Bispebjerg Hospital, 2400 København NV, Denmark. kkof0013@bbh.regionh.dk
    • Ugeskr. Laeg. 2011 Jan 10;173(2):110-4.

    AbstractHerpes zoster (HZ) and post-herpetic neuralgia (PHN) are frequently occurring diseases in elderly and in immuno-compromised persons. The live attenuated HZ vaccine boosts an existing immune response, so that the already established varicella-zoster virus infection is kept latent. Vaccination has been shown to halve the risk of HZ, and the risk of PHN is reduced by two thirds in people = 60 years. The vaccine is approved for persons aged = 50 years. However, the clinical efficacy of the vaccine is best studied in people aged = 60 years. The vaccine has so far not shown any serious side-effects.

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