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Case Reports
Pre-emptive metoclopramide and ondansetron for nausea and vomiting associated with iloprost infusions.
- C Roome and J Thompson.
- Royal Devon & Exeter Hospital (Wonford), Barrack Road, Exeter, England EX2 5DW, UK.
- Pharm World Sci. 2001 Jun 1;23(3):122.
ObjectiveTo assess the effectiveness of ondansetron in relieving symptoms of nausea and vomiting which were refractory to metoclopramide and cyclizine, in a patient receiving iloprost infusions.MethodCase observation in a series of 7 infusions.ResultsOndansetron reduced WHO symptom scores of vomiting from Grade 2 to Grade 0. Symptoms of nausea were abolished on some occasions.ConclusionOndansetron was found to be effective at abolishing symptoms of vomiting and partially effective against symptoms of nausea. It may prove to be a useful treatment modality to allow the patient to tolerate further infusions of iloprost where nausea and vomiting has failed to respond to other agents.
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