• Anaesthesia · Jul 2012

    Review Meta Analysis

    Use of plethysmographic variability index derived from the Massimo(®) pulse oximeter to predict fluid or preload responsiveness: a systematic review and meta-analysis.

    • J Y Yin and K M Ho.
    • Department of Surgery, Nanjing University School of Medicine, Nanjing, China.
    • Anaesthesia. 2012 Jul 1;67(7):777-83.

    AbstractThis systematic review and meta-analysis assessed the accuracy of plethysmographic variability index derived from the Massimo(®) pulse oximeter to predict preload responsiveness in peri-operative and critically ill patients. A total of 10 studies were retrieved from the literature, involving 328 patients who met the selection criteria. Overall, the diagnostic odds ratio (16.0; 95% CI 5-48) and area under the summary receiver operating characteristic curve (0.87; 95% CI 0.78-0.95) for plethysmographic variability index to predict fluid or preload responsiveness was very good, but significant heterogeneity existed. This could be explained by a lower accuracy of plethysmographic variability index in spontaneously breathing or paediatric patients and those studies that used pre-load challenges other than colloid fluid. The results indicate specific directions for future studies.Anaesthesia © 2012 The Association of Anaesthetists of Great Britain and Ireland.

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