• Biotechnol. Appl. Biochem. · Jun 2004

    Review

    Tissue-engineered skin substitutes: from in vitro constructs to in vivo applications.

    • François A Auger, François Berthod, Véronique Moulin, Roxane Pouliot, and Lucie Germain.
    • Laboratoire d'Organogénèse Expérimentale/LOEX, Saint-Sacrement Hospital, and Department of Surgery, Faculty of Medicine, Laval University, Québec, QC, Canada G1S 4L8. francois.auger@chg.ulaval.ca
    • Biotechnol. Appl. Biochem. 2004 Jun 1;39(Pt 3):263-75.

    AbstractThe field of skin tissue engineering is a paradigm for the various efforts towards the reconstruction of other tissues and organ substitutes. As skin replacement, this biotechnological approach has evolved from simple cultured autologous epidermal sheets to more complex bilayered cutaneous substitutes. The various types of such substitutes are herein presented with their intended use. However, two integrative characteristics are analysed more specifically because of their critical role: neovascularization and re-innervation. Furthermore, the in vitro use of these various skin substitutes has shed light on various physiological and pathological phenomena. Thus, not only the in vivo application of these skin substitutes as grafts, but also their in vitro value as skin models, are presented.

      Pubmed     Full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…