• British medical journal · Jul 1979

    Randomized Controlled Trial Comparative Study Clinical Trial

    Postoperative analgesia: a comparison of intravenous on-demand fentanyl with epidural bupivacaine.

    • W D White, D J Pearce, and J Norman.
    • Br Med J. 1979 Jul 21;2(6183):166-7.

    AbstractIn a randomised trial postoperative pain relief was provided by either epidural injections of bupivacaine or an infusion of fentanyl adjusted by the patient to achieve adequate pain relief. Both techniques produced satisfactory analgesia without respiratory depression after peripheral arterial surgery. The technique of infusing intravenously a potent analgesic in a dose adjusted by the patient appears to offer several advantages in postoperative care.

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