• Respir Care Clin N Am · Sep 2004

    Review

    Therapy for ventilator-associated pneumonia: what works, what doesn't.

    • Mohammed Hijazi and Mariam Al-Ansari.
    • Section of Critical Care Medicine, Department of Medicine, (MBC-46), King Faisal Specialist Hospital and Research Centre, P.O. Box 3354, Riyadh 11211, Saudi Arabia. hijazim@hotmail.com
    • Respir Care Clin N Am. 2004 Sep 1;10(3):341-58, vi.

    AbstractVentilator-associated pneumonia is a common cause of morbidity and mortality in critically ill patients. Inappropriate initial antimicrobial therapy is associated with poor outcome. An initial aggressive strategy using broad-spectrum antibiotics based on the local distribution of pathogens, patient risk factors, and antimicrobial characteristics; followed by focused therapy based on microbiologic studies, will help minimize the chance of inappropriate therapy and the emergence of resistance.

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