• Kidney international · Sep 2011

    Comment

    The challenges of assessing acute kidney injury in infants.

    • Guido M Filler.
    • Department of Pediatrics, Schulich School of Medicine and Dentistry, London, Ontario, Canada. guido.filler@lhsc.on.ca
    • Kidney Int. 2011 Sep 1;80(6):567-8.

    AbstractDefinitions of pediatric acute kidney injury (AKI) use changes of serum creatinine. There is a paucity of well-designed studies in infants because of creatinine age-dependency. The emerging role of cystatin C as a superior marker of renal dysfunction led to a carefully conducted study on AKI in infants by Zappitelli et al. This Commentary calls for the development of age-independent serum creatinine and estimated glomerular filtration rate z scores.

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