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Thoracic surgery clinics · May 2015
Randomized Controlled Trial Multicenter Study Comparative StudyResults of the national lung cancer screening trial: where are we now?
- Neel P Chudgar, Peter R Bucciarelli, Elizabeth M Jeffries, Nabil P Rizk, Bernard J Park, Prasad S Adusumilli, and David R Jones.
- Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
- Thorac Surg Clin. 2015 May 1;25(2):145-53.
AbstractThe National Lung Screening Trial was a large, multicenter, randomized controlled trial published in 2011. It found that annual screening with low-dose CT (LDCT) in a high-risk population was associated with a 20% reduction in lung cancer-specific mortality compared with conventional chest radiography. Several leading professional organizations have since put forth lung cancer screening guidelines that include the use of LDCT, largely on the basis of this study. Broad adoption of these screening recommendations, however, remains a challenge.Copyright © 2015 Elsevier Inc. All rights reserved.
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