• Oncology Ny · Sep 2007

    Review

    Practical guide to opioids and their complications in managing cancer pain. What oncologists need to know.

    • Mellar P Davis, Wael Lasheen, and Pamela Gamier.
    • The Harry R. Horvitz Center for Palliative Medicine, Cleveland Clinic, Taussig Cancer Center, Cleveland, Ohio 44195, USA. davism6@ccf.org
    • Oncology Ny. 2007 Sep 1;21(10):1229-38; discussion 1238-46, 1249.

    AbstractApproximately 60% of cancer patients experience pain, and 25% to 30% have severe pain. With some cancers, opioids will be needed before chemotherapy begins and may be more frequently prescribed than chemotherapy. Given the frequency with which pain management is necessary in cancer patients, all oncologists should be familiar with opioid prescribing principles. This article reviews the World Health Organization recommendations for analgesic therapy in this setting, as well as guidelines for opioid therapy in patients with renal failure or hepatic failure, assessment of pain, dosing strategies in both acute and chronic pain, management of opioid overdose, pain associated with dose-limiting side effects, and pain in the actively dying.

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