• Br J Anaesth · Jan 1982

    Comparative Study

    Alfentanil: a study of its analgesic activity and interactions with morphine in the mouse.

    • J G Williams, J H Brown, and B J Pleuvry.
    • Br J Anaesth. 1982 Jan 1;54(1):81-5.

    AbstractAlfentanil has a short duration action which did not markedly increase with increasing dose in mice. It is approximately one-fourth as potent as fentanyl. Repeat injections gave reproducible analgesic effects but depression of respiratory rate increased when repeat injections were given on the basis of cessation of analgesic activity. Alfentanil appeared to reduce the analgesic effect of morphine given 30-60 min after alfentanil administration. This has been demonstrated with injection of alfentanil 15 min before, simultaneously with and 30 min after morphine injection. There were not significant effects on depression of respiratory rate produce by morphine.

      Pubmed     Full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…