• Paediatric anaesthesia · Dec 2005

    Case Reports

    Severe hepatotoxicity after sevoflurane anesthesia in a child with mild renal dysfunction.

    • Youngho Jang and Insoo Kim.
    • Department of Anesthesiology and Pain Medicine, School of Medicine, Keimyung University, Daegu, Korea. weonjo@dsmc.or.kr
    • Paediatr Anaesth. 2005 Dec 1;15(12):1140-4.

    AbstractSevoflurane, an anesthetic agent with methyl isopropyl fluorinated ether structure, has a very low potential for hepatotoxicity. Nevertheless, a few cases of hepatotoxicity have been reported since its introduction into clinical practice. The underlying pathophysiology may be multifactorial and sometimes nonspecific. We report a case of severe hepatotoxicity after anesthesia with sevoflurane in a child with preexisting mild renal dysfunction.

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