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Antimicrob. Agents Chemother. · Oct 2015
In Vitro Activities of Eight Antifungal Drugs against a Global Collection of Genotyped Exserohilum Isolates.
- Anuradha Chowdhary, Ferry Hagen, Ilse Curfs-Breuker, Hugo Madrid, G Sybren de Hoog, and Jacques F Meis.
- Department of Medical Mycology, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India.
- Antimicrob. Agents Chemother. 2015 Oct 1; 59 (10): 6642-5.
AbstractThe in vitro susceptibilities of 24 worldwide Exserohilum isolates belonging to 10 species from human and environmental sources were determined for eight antifungal drugs. The strains were characterized by internal transcribed spacer (ITS) sequencing and amplified fragment length polymorphism fingerprinting. Posaconazole had the lowest geometric mean MIC (0.16 μg/ml), followed by micafungin (0.21 μg/ml), amphotericin B (0.24 μg/ml), itraconazole (0.33 μg/ml), voriconazole (0.8 μg/ml), caspofungin (1.05 μg/ml), isavuconazole (1.38 μg/ml), and fluconazole (15.6 μg/ml).Copyright © 2015, American Society for Microbiology. All Rights Reserved.
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