• HPB (Oxford) · Oct 2014

    Multicenter Study

    Defining the post-operative morbidity index for distal pancreatectomy.

    • Major K Lee, Russell S Lewis, Steven M Strasberg, Bruce L Hall, John D Allendorf, Joal D Beane, Stephen W Behrman, Mark P Callery, John D Christein, Jeffrey A Drebin, Irene Epelboym, Jin He, Henry A Pitt, Emily Winslow, Christopher Wolfgang, and Charles M Vollmer.
    • Department of Surgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA; Department of Surgery, Washington University in St. Louis School of Medicine, MO, USA.
    • HPB (Oxford). 2014 Oct 1;16(10):915-23.

    BackgroundAccurate assessment of complications is critical in analysing surgical outcomes. The post-operative morbidity index (PMI), derived from the Modified Accordion Severity Grading System and American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP), is a quantitative measure of post-operative morbidity. This study utilizes PMI to establish the complication burden for a distal pancreatectomy (DP).MethodsFrom 2005-2011, nine centres contributed ACS-NSQIP complication data for 655 DPs. Each complication was assigned an Accordion severity weight ranging from 0.11 for grade 1 to 1.00 for grade 6 (death). The PMI is the sum of complication severity weights divided by the total number of patients.ResultsACS-NSQIP complications occurred in 177 patients (27.0%). The non risk-adjusted PMI for DP is 0.087. Bleeding/Transfusion and Organ Space Infection were the most common complications. Frequency and burden differed across Accordion grades. While grade 4-6 complications represented only 15.4% of complication occurrences, they accounted for 30.4% of the burden. Subgroup analysis demonstrates that the PMI did not vary based on laparoscopic versus open approach or the performance of a splenectomy.DiscussionThis study uses two validated systems to quantitatively establish the morbidity of a DP. The PMI allows estimation of both the frequency and severity of complications and thus provides a more comprehensive assessment of risk.© 2014 International Hepato-Pancreato-Biliary Association.

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